21  The Issues of \(p\)-value and Statistical Significance

Our brain has this annoying habit to think that […], if under some hypothesis, results are unlikely, then the hypothesis is unlikely. This is false. – Christophe Michel (1974 - )

There are three types of lies: lies, damn lies, and statistics. – Benjamin Disraeli (1804 - 1881)

We have been using the classical or frequentist approach to do a variety of statistical inferences. But Dr. Yu once said he never uses p-value in his own research, and there are many issues with what is taught in Intro Stats (MATH 1700/4720/4740). In fact, the null hypothesis significance testing (NHST) paradigm and the p-value usage have been much criticized and shown to be problematic, misused, and resulting in reproducibility and replication crisis in scientific research.

Some references are